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bFGF Drug R&D Technology
Basic  fibroblast  growth  factor ( bFGF ) is an  active  substance in  trace  amount existing in mammals and human body, which  can  promote the  repair  and  regeneration of  cells  derived  from the  mesoderm and ectoderm (such as epithelial cells,  dermis cells,  fibroblasts,  endothelial  cells,  osteocytes,  chondrocytes, neurons and glial cells etc.).  Therefore,bFGF has a wide range of  physiological functions and is of great value for clinical application.

1)

bFGF Recombinant DNA Technology
  Biochemical extraction of bFGF is extremely difficult. The extraction of 1gram of bFGF needs approximately 10,000 cattle.?The company has successfully  modified and recombined the bovine bFGF and human bFGF based on the recombinant DNA technology, and obtained the highly effective expression plasmids of rb-bFGF and rh-bFGF and engineering bacteria for production, which has provided the conditions for industrialized production of bFGF.
   
2) bFGF Large-scale Production Process and Quality Control Technology
  The company has developed and mastered the manufacturing technology for the high-density fermentation of rb-bFGF and rh-bFGF engineering bacteria, and the separation and purification of proteins.  It has satisfied the requirement for large-scale production of rb-bFGF and rh-bFGF. A complete rb-bFGF and rh-bFGF raw liquid quality control system has been established.
 
3) bFGF Formulation Research and Production Technology
  The company has developed and mastered a series of  core technologies including rb-bFGF and rh-bFGF formulations, production process and stability technology. Five rb-bFGF formulations have been successfully developed for the treatment of body surface wounds and eye injuries. Other bFGF new products are under development for the treatment of other wounded conditions.
 
 

 

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